Hippocampal Regulation of Stress Vulnerability & Resilience
Christoph Anacker
Columbia University Medical Center
Abstract
The hippocampus is a crucial brain region for stress response regulation that has been implicated in a wide range of cognitive functions and emotional behaviors. However, the cell types and molecular mechanisms within the hippocampus that regulate vulnerability to stress are poorly understood. Dr. Anacker will discuss cellular and molecular mechanisms within the dentate gyrus region of the ventral hippocampus that determine individual differences in stress susceptibility and resilience with a particular focus on the long-lasting effects of early life adversity on the serotonergic regulation of neurogenesis, granule cell activity, and neuroendocrine function in rodent models.
ORGANIZERS
Nesha Burghardt, Hunter College, CUNY
Asohan Amarasingham, City College of New York, CUNY