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Hippocampal Regulation of Stress Vulnerability & Resilience

  • Rm 6495, CUNY Graduate Center 365 5th Avenue New York, NY, 10016 United States (map)

Hippocampal Regulation of Stress Vulnerability & Resilience

Christoph Anacker

Columbia University Medical Center


Abstract

The hippocampus is a crucial brain region for stress response regulation that has been implicated in a wide range of cognitive functions and emotional behaviors. However, the cell types and molecular mechanisms within the hippocampus that regulate vulnerability to stress are poorly understood. Dr. Anacker will discuss cellular and molecular mechanisms within the dentate gyrus region of the ventral hippocampus that determine individual differences in stress susceptibility and resilience with a particular focus on the long-lasting effects of early life adversity on the serotonergic regulation of neurogenesis, granule cell activity, and neuroendocrine function in rodent models.


ORGANIZERS

Nesha Burghardt, Hunter College, CUNY

Asohan Amarasingham, City College of New York, CUNY